The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions

Background Many platelet (PLT) transfusion trials now use bleeding as a primary outcome; however, previous studies have shown a wide variation in the amount (5%-70%) and type of bleeding documented. Differences in the way bleeding has been identified, recorded, and graded may account for some of thi...

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Autori principali: Estcourt, L, Heddle, N, Kaufman, R, McCullough, J, Murphy, M, Slichter, S, Wood, E, Stanworth, S
Natura: Journal article
Lingua:English
Pubblicazione: 2013