FEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning

The ability to adapt medical image segmentation networks for a novel class such as an unseen anatomical or pathological structure, when only a few labelled examples of this class are available from local healthcare providers, is sought-after. This potentially addresses two widely recognised limitati...

Full description

Bibliographic Details
Main Authors: Li, Y, Fu, Y, Yang, Q, Min, Z, Yan, W, Huisman, H, Barratt, D, Prisacariu, VA, Hu, Y
Format: Conference item
Language:English
Published: IEEE 2022
_version_ 1826311841516617728
author Li, Y
Fu, Y
Yang, Q
Min, Z
Yan, W
Huisman, H
Barratt, D
Prisacariu, VA
Hu, Y
author_facet Li, Y
Fu, Y
Yang, Q
Min, Z
Yan, W
Huisman, H
Barratt, D
Prisacariu, VA
Hu, Y
author_sort Li, Y
collection OXFORD
description The ability to adapt medical image segmentation networks for a novel class such as an unseen anatomical or pathological structure, when only a few labelled examples of this class are available from local healthcare providers, is sought-after. This potentially addresses two widely recognised limitations in deploying modern deep learning models to clinical practice, expertise-and-labour-intensive labelling and cross-institution generalisation. This work presents the first 3D few-shot interclass segmentation network for medical images, using a labelled multi-institution dataset from prostate cancer patients with eight regions of interest. We propose an image alignment module registering the predicted segmentation of both query and support data, in a standard prototypical learning algorithm, to a reference atlas space. The built-in registration mechanism can effectively utilise the prior knowledge of consistent anatomy between subjects, regardless whether they are from the same institution or not. Experimental results demonstrated that the proposed registration-assisted prototypical learning significantly improved segmentation accuracy (p-values<0.01) on query data from a holdout institution, with varying availability of support data from multiple institutions. We also report the additional benefits of the proposed 3D networks with 75% fewer parameters and an arguably simpler implementation, compared with existing 2D few-shot approaches that segment 2D slices of volumetric medical images.
first_indexed 2024-03-07T08:17:14Z
format Conference item
id oxford-uuid:72596c63-5217-4b37-8735-107336497b86
institution University of Oxford
language English
last_indexed 2024-03-07T08:17:14Z
publishDate 2022
publisher IEEE
record_format dspace
spelling oxford-uuid:72596c63-5217-4b37-8735-107336497b862024-01-11T14:18:02ZFEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learningConference itemhttp://purl.org/coar/resource_type/c_5794uuid:72596c63-5217-4b37-8735-107336497b86EnglishSymplectic ElementsIEEE2022Li, YFu, YYang, QMin, ZYan, WHuisman, HBarratt, DPrisacariu, VAHu, YThe ability to adapt medical image segmentation networks for a novel class such as an unseen anatomical or pathological structure, when only a few labelled examples of this class are available from local healthcare providers, is sought-after. This potentially addresses two widely recognised limitations in deploying modern deep learning models to clinical practice, expertise-and-labour-intensive labelling and cross-institution generalisation. This work presents the first 3D few-shot interclass segmentation network for medical images, using a labelled multi-institution dataset from prostate cancer patients with eight regions of interest. We propose an image alignment module registering the predicted segmentation of both query and support data, in a standard prototypical learning algorithm, to a reference atlas space. The built-in registration mechanism can effectively utilise the prior knowledge of consistent anatomy between subjects, regardless whether they are from the same institution or not. Experimental results demonstrated that the proposed registration-assisted prototypical learning significantly improved segmentation accuracy (p-values<0.01) on query data from a holdout institution, with varying availability of support data from multiple institutions. We also report the additional benefits of the proposed 3D networks with 75% fewer parameters and an arguably simpler implementation, compared with existing 2D few-shot approaches that segment 2D slices of volumetric medical images.
spellingShingle Li, Y
Fu, Y
Yang, Q
Min, Z
Yan, W
Huisman, H
Barratt, D
Prisacariu, VA
Hu, Y
FEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning
title FEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning
title_full FEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning
title_fullStr FEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning
title_full_unstemmed FEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning
title_short FEW-SHOT image segmentation for cross-institution male pelvic organs using registration-assisted prototypical learning
title_sort few shot image segmentation for cross institution male pelvic organs using registration assisted prototypical learning
work_keys_str_mv AT liy fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT fuy fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT yangq fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT minz fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT yanw fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT huismanh fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT barrattd fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT prisacariuva fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning
AT huy fewshotimagesegmentationforcrossinstitutionmalepelvicorgansusingregistrationassistedprototypicallearning