The immunology of infection
The human immune system is composed of a collection of specialized cells and secreted proteins that allows the identification and removal of an invading pathogen, and in doing so limits host injury or death. This system is composed of innate and adaptive branches. It is important to recognize that a...
主要な著者: | , |
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フォーマット: | Journal article |
出版事項: |
Elsevier
2017
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_version_ | 1826278870862528512 |
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author | Gilchrist, J MacLennan, C |
author_facet | Gilchrist, J MacLennan, C |
author_sort | Gilchrist, J |
collection | OXFORD |
description | The human immune system is composed of a collection of specialized cells and secreted proteins that allows the identification and removal of an invading pathogen, and in doing so limits host injury or death. This system is composed of innate and adaptive branches. It is important to recognize that although the innate and adaptive branches of the immune system differ fundamentally in their mechanisms of pathogen recognition, neither branch functions in isolation. In this article, we address how the innate and adaptive immune systems sense the presence of a pathogen, how the immune system then coordinates anti-pathogen effector functions to remove the pathogen, and finally how immunological memory functions to better protect its host against subsequent exposure to the same pathogen. |
first_indexed | 2024-03-06T23:50:25Z |
format | Journal article |
id | oxford-uuid:72697085-31f5-45ff-9561-394c2aafcd3d |
institution | University of Oxford |
last_indexed | 2024-03-06T23:50:25Z |
publishDate | 2017 |
publisher | Elsevier |
record_format | dspace |
spelling | oxford-uuid:72697085-31f5-45ff-9561-394c2aafcd3d2022-03-26T19:49:58ZThe immunology of infectionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:72697085-31f5-45ff-9561-394c2aafcd3dSymplectic Elements at OxfordElsevier2017Gilchrist, JMacLennan, CThe human immune system is composed of a collection of specialized cells and secreted proteins that allows the identification and removal of an invading pathogen, and in doing so limits host injury or death. This system is composed of innate and adaptive branches. It is important to recognize that although the innate and adaptive branches of the immune system differ fundamentally in their mechanisms of pathogen recognition, neither branch functions in isolation. In this article, we address how the innate and adaptive immune systems sense the presence of a pathogen, how the immune system then coordinates anti-pathogen effector functions to remove the pathogen, and finally how immunological memory functions to better protect its host against subsequent exposure to the same pathogen. |
spellingShingle | Gilchrist, J MacLennan, C The immunology of infection |
title | The immunology of infection |
title_full | The immunology of infection |
title_fullStr | The immunology of infection |
title_full_unstemmed | The immunology of infection |
title_short | The immunology of infection |
title_sort | immunology of infection |
work_keys_str_mv | AT gilchristj theimmunologyofinfection AT maclennanc theimmunologyofinfection AT gilchristj immunologyofinfection AT maclennanc immunologyofinfection |