Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats.
We have used the whole-cell recording technique to determine whether ATP-sensitive potassium (K[ATP]) currents, voltage-dependent Ca2+ currents, and exocytosis are different in single beta-cells from pancreatic islets of Goto-Kakizaki (GK) rats, a novel model of NIDDM, and normal rats. In addition,...
المؤلفون الرئيسيون: | Hughes, S, Faehling, M, Thorneley, C, Proks, P, Ashcroft, F, Smith, P |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1998
|
مواد مشابهة
-
Metformin restores electrophysiology of small conductance calcium-activated potassium channels in the atrium of GK diabetic rats
حسب: Xi Fu, وآخرون
منشور في: (2018-04-01) -
Electrophysiology of the pancreatic beta-cell.
حسب: Ashcroft, F, وآخرون
منشور في: (1989) -
DIFFERENT TYPES OF MEMBRANE RETRIEVAL IN SINGLE-MOUSE PANCREATIC BETA-CELLS
حسب: Proks, P, وآخرون
منشور في: (1995) -
Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.
حسب: Albert Salehi, وآخرون
منشور في: (2008-05-01) -
Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
منشور في: (2008-01-01)