Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats.

Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats.

We have used the whole-cell recording technique to determine whether ATP-sensitive potassium (K[ATP]) currents, voltage-dependent Ca2+ currents, and exocytosis are different in single beta-cells from pancreatic islets of Goto-Kakizaki (GK) rats, a novel model of NIDDM, and normal rats. In addition,...

书目详细资料
Main Authors:	Hughes, S, Faehling, M, Thorneley, C, Proks, P, Ashcroft, F, Smith, P
格式:	Journal article
语言:	English
出版:	1998

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