Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats.

We have used the whole-cell recording technique to determine whether ATP-sensitive potassium (K[ATP]) currents, voltage-dependent Ca2+ currents, and exocytosis are different in single beta-cells from pancreatic islets of Goto-Kakizaki (GK) rats, a novel model of NIDDM, and normal rats. In addition,...

詳細記述

書誌詳細
主要な著者: Hughes, S, Faehling, M, Thorneley, C, Proks, P, Ashcroft, F, Smith, P
フォーマット: Journal article
言語:English
出版事項: 1998