A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment
Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...
Main Authors: | Wegmann, F, Krashias, G, Lühn, K, Laamanen, K, Vieira, S, Jeffs, S, Shattock, R, Sattentau, Q |
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Formato: | Journal article |
Idioma: | English |
Publicado: |
Public Library of Science
2011
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Subjects: |
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