A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

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Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...

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Bibliografiske detaljer
Main Authors:	Wegmann, F, Krashias, G, Lühn, K, Laamanen, K, Vieira, S, Jeffs, S, Shattock, R, Sattentau, Q
Format:	Journal article
Sprog:	English
Udgivet:	Public Library of Science 2011
Fag:	Pathology HIV/AIDS

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