A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

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Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...

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Main Authors: Wegmann, F, Krashias, G, Lühn, K, Laamanen, K, Vieira, S, Jeffs, S, Shattock, R, Sattentau, Q
פורמט: Journal article
שפה:English
יצא לאור: Public Library of Science 2011
נושאים:
Pathology
HIV/AIDS
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