A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Wegmann, F, Krashias, G, Lühn, K, Laamanen, K, Vieira, S, Jeffs, S, Shattock, R, Sattentau, Q
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Public Library of Science 2011
Những chủ đề: