CD6 as a cell surface receptor and as a target for regulating immune responses.
CD6 has been exploited as a drug target as its expression is restricted, primarily to T cells, it has a well characterised cell surface ligand, CD166 and regulates T cell activation through a long cytoplasmic tail. CD6 can affect both the initiation and maintenance of T cell function in a negative a...
Autor Principal: | |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado: |
Bentham Science
2016
|