CD6 as a cell surface receptor and as a target for regulating immune responses.

CD6 has been exploited as a drug target as its expression is restricted, primarily to T cells, it has a well characterised cell surface ligand, CD166 and regulates T cell activation through a long cytoplasmic tail. CD6 can affect both the initiation and maintenance of T cell function in a negative a...

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Detalles Bibliográficos
Autor Principal: Brown, M
Formato: Journal article
Idioma:English
Publicado: Bentham Science 2016