Asymmetric synthesis of (-)-(R)-sitagliptin

Asymmetric synthesis of (-)-(R)-sitagliptin

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The asymmetric synthesis of (-)-(R)-sitagliptin was achieved in seven steps from commercially available starting materials using the highly diastereoselective conjugate additions of either lithium (R)-N-benzyl-N- (α-methylbenzyl)amide or lithium (R)-N-benzyl-N-(α-methyl-p- methoxybenzyl)amide to ter...

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Main Authors: Davies, S, Fletcher, A, Lv, L, Roberts, P, Thomson, J
פורמט: Journal article
יצא לאור: 2012
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Asymmetric synthesis of (-)-(R)-sitagliptin

Asymmetric synthesis of (-)-(R)-sitagliptin מאת Davies, S, Fletcher, A, Lv, L, Roberts, P, Thomson, J

יצא לאור 2012
Journal article
Search Result 2
Asymmetric synthesis of (-)-(R)-sitagliptin

Asymmetric synthesis of (-)-(R)-sitagliptin מאת Davies, S, Fletcher, A, Lv, L, Roberts, P, Thomson, J

יצא לאור 2012
Journal article
Show all versions (3)

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