Biomarker report from the phase II lamotrigine trial in secondary progressive MS - neurofilament as a surrogate of disease progression

Objective Lamotrigine trial in SPMS was a randomised control trial to assess whether partial blockade of sodium channels has a neuroprotective effect. The current study was an additional study to investigate the value of neurofilament (NfH) and other biomarkers in predicting prognosis and/or respons...

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Main Authors: Gnanapavan, S, Grant, D, Morant, S, Furby, J, Hayton, T, Teunissen, C, Leoni, V, Marta, M, Brenner, R, Palace, J, Miller, D, Kapoor, R, Giovannoni, G
Format: Journal article
Language:English
Published: Public Library of Science 2013