Travel risk, malaria importation and malaria transmission in Zanzibar

<br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">The prevalence of Plasmodium falciparum malaria in Zanzibar has reached historic lows. Improving control requires quantifying malaria importation rates, identifying high-risk travelers and assessing onwards transmission.<...

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Main Authors: Le Menach, A, Tatem, A, Cohen, J, Hay, S, Randell, H, Patil, A, Smith, D
Format: Journal article
Language:English
Published: Springer Nature 2011
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author Le Menach, A
Tatem, A
Cohen, J
Hay, S
Randell, H
Patil, A
Smith, D
author_facet Le Menach, A
Tatem, A
Cohen, J
Hay, S
Randell, H
Patil, A
Smith, D
author_sort Le Menach, A
collection OXFORD
description <br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">The prevalence of Plasmodium falciparum malaria in Zanzibar has reached historic lows. Improving control requires quantifying malaria importation rates, identifying high-risk travelers and assessing onwards transmission.</br> <br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Estimates of Zanzibar's importation rate were calculated through two independent methodologies. First, mobile phone usage data and ferry traffic between Zanzibar and mainland Tanzania were re-analyzed using a model of heterogeneous travel risk. Second, a dynamic mathematical model of importation and transmission rates was used.</br> <br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Zanzibar residents traveling to malaria endemic regions were estimated to contribute 1–15 times more imported cases than infected visitors. The malaria importation rate was estimated to be 1.6 incoming infections per 1,000 inhabitants per year. Local transmission was estimated too low to sustain transmission in most places.</br> <br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Malaria infections in Zanzibar largely result from imported malaria and subsequent transmission. Plasmodium falciparum malaria elimination appears feasible by implementing control measures based on detecting imported malaria cases and controlling onward transmission.</br>
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spelling oxford-uuid:72eef720-bf91-4764-8fc2-fe3130846b212022-03-26T19:53:18ZTravel risk, malaria importation and malaria transmission in ZanzibarJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:72eef720-bf91-4764-8fc2-fe3130846b21EnglishSymplectic Elements at OxfordSpringer Nature2011Le Menach, ATatem, ACohen, JHay, SRandell, HPatil, ASmith, D<br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">The prevalence of Plasmodium falciparum malaria in Zanzibar has reached historic lows. Improving control requires quantifying malaria importation rates, identifying high-risk travelers and assessing onwards transmission.</br> <br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Estimates of Zanzibar's importation rate were calculated through two independent methodologies. First, mobile phone usage data and ferry traffic between Zanzibar and mainland Tanzania were re-analyzed using a model of heterogeneous travel risk. Second, a dynamic mathematical model of importation and transmission rates was used.</br> <br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Zanzibar residents traveling to malaria endemic regions were estimated to contribute 1–15 times more imported cases than infected visitors. The malaria importation rate was estimated to be 1.6 incoming infections per 1,000 inhabitants per year. Local transmission was estimated too low to sustain transmission in most places.</br> <br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Malaria infections in Zanzibar largely result from imported malaria and subsequent transmission. Plasmodium falciparum malaria elimination appears feasible by implementing control measures based on detecting imported malaria cases and controlling onward transmission.</br>
spellingShingle Le Menach, A
Tatem, A
Cohen, J
Hay, S
Randell, H
Patil, A
Smith, D
Travel risk, malaria importation and malaria transmission in Zanzibar
title Travel risk, malaria importation and malaria transmission in Zanzibar
title_full Travel risk, malaria importation and malaria transmission in Zanzibar
title_fullStr Travel risk, malaria importation and malaria transmission in Zanzibar
title_full_unstemmed Travel risk, malaria importation and malaria transmission in Zanzibar
title_short Travel risk, malaria importation and malaria transmission in Zanzibar
title_sort travel risk malaria importation and malaria transmission in zanzibar
work_keys_str_mv AT lemenacha travelriskmalariaimportationandmalariatransmissioninzanzibar
AT tatema travelriskmalariaimportationandmalariatransmissioninzanzibar
AT cohenj travelriskmalariaimportationandmalariatransmissioninzanzibar
AT hays travelriskmalariaimportationandmalariatransmissioninzanzibar
AT randellh travelriskmalariaimportationandmalariatransmissioninzanzibar
AT patila travelriskmalariaimportationandmalariatransmissioninzanzibar
AT smithd travelriskmalariaimportationandmalariatransmissioninzanzibar