Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes.

AIMS: Type 2 diabetes mellitus is frequently associated with hypertension, but the underlying mechanisms are not completely understood. We tested the hypothesis that activation of type 1 prostaglandin E(2) (PGE(2)) receptor (EP1) increases skeletal muscle arteriolar tone and blood pressure in mice...

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Bibliographic Details
Main Authors: Rutkai, I, Feher, A, Erdei, N, Henrion, D, Papp, Z, Edes, I, Koller, A, Kaley, G, Bagi, Z
Format: Journal article
Language:English
Published: 2009