CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.
The chemokine eotaxin/CCL11 is an important mediator of leukocyte migration, but its effect on inflammatory cytokine signaling has not been explored. In this study, we find that CCL11 induces suppressor of cytokine signaling (SOCS)1 and SOCS3 expression in murine macrophages, human monocytes, and de...
Հիմնական հեղինակներ: | Stevenson, N, Addley, MR, Ryan, E, Boyd, C, Carroll, H, Paunovic, V, Bursill, C, Miller, H, Channon, K, McClurg, A, Armstrong, M, Coulter, W, Greaves, D, Johnston, J |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2009
|
Նմանատիպ նյութեր
-
Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11.
: Stevenson, N, և այլն
Հրապարակվել է: (2010) -
GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors
: Bianca Calì, և այլն
Հրապարակվել է: (2021-10-01) -
JAK inhibitors impair GM-CSF-mediated signaling in innate immune cells
: Yuya Fujita, և այլն
Հրապարակվել է: (2020-06-01) -
GM-CSF signalling boosts dramatically IL-1 production.
: Hanif Javanmard Khameneh, և այլն
Հրապարակվել է: (2011-01-01) -
Development of Dendritic Cells from GM-CSF-/-Mice invitro : GM-CSF Enhances Productionand Survival of Cells
: Keping Ni, և այլն
Հրապարակվել է: (2001-01-01)