CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.

CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.

The chemokine eotaxin/CCL11 is an important mediator of leukocyte migration, but its effect on inflammatory cytokine signaling has not been explored. In this study, we find that CCL11 induces suppressor of cytokine signaling (SOCS)1 and SOCS3 expression in murine macrophages, human monocytes, and de...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Stevenson, N, Addley, MR, Ryan, E, Boyd, C, Carroll, H, Paunovic, V, Bursill, C, Miller, H, Channon, K, McClurg, A, Armstrong, M, Coulter, W, Greaves, D, Johnston, J
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2009

Míreanna comhchosúla

Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11.
de réir: Stevenson, N, et al.
Foilsithe / Cruthaithe: (2010)

JAK inhibitors impair GM-CSF-mediated signaling in innate immune cells
de réir: Yuya Fujita, et al.
Foilsithe / Cruthaithe: (2020-06-01)

Development of Dendritic Cells from GM-CSF-/-Mice invitro : GM-CSF Enhances Productionand Survival of Cells
de réir: Keping Ni, et al.
Foilsithe / Cruthaithe: (2001-01-01)

Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function
de réir: Eliana Ribechini, et al.
Foilsithe / Cruthaithe: (2017-06-01)

Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
de réir: Bryan D. Bryson, et al.
Foilsithe / Cruthaithe: (2019-05-01)

Suppressor of cytokine signalling protein SOCS3 expression is increased at sites of acute and chronic inflammation.
de réir: White, G, et al.
Foilsithe / Cruthaithe: (2011)

GM‐CSF signalling in Th17‐cell pathogenicity: The culprit in autoimmune uveitis promoted by sleep loss
de réir: Chun Zhang, et al.
Foilsithe / Cruthaithe: (2023-06-01)

Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders
de réir: Hillard M. Lazarus, et al.
Foilsithe / Cruthaithe: (2023-01-01)

Senescent cells promote breast cancer cells motility by secreting GM-CSF and bFGF that activate the JNK signaling pathway
de réir: Nan Wang, et al.
Foilsithe / Cruthaithe: (2024-10-01)

Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes
de réir: Ramon M. Rodriguez, et al.
Foilsithe / Cruthaithe: (2019-10-01)

GM-CSF Promotes the Expansion and Differentiation of Cord Blood Myeloid-Derived Suppressor Cells, Which Attenuate Xenogeneic Graft-vs.-Host Disease
de réir: Mi-Young Park, et al.
Foilsithe / Cruthaithe: (2019-02-01)

GM-CSF Monocyte-Derived Cells and Langerhans Cells As Part of the Dendritic Cell Family
de réir: Manfred B. Lutz, et al.
Foilsithe / Cruthaithe: (2017-10-01)

Immune Evasion of G-CSF and GM-CSF in Lung Cancer
de réir: Yeonhee Park, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Gene Regulatory Network of Human GM-CSF-Secreting T Helper Cells
de réir: Szabolcs Éliás, et al.
Foilsithe / Cruthaithe: (2021-01-01)

Whole tumor cell vaccines engineered to secrete GM‐CSF (GVAX)
de réir: Robert J. Soiffer, et al.
Foilsithe / Cruthaithe: (2021-06-01)

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.
de réir: Alissa C Rothchild, et al.
Foilsithe / Cruthaithe: (2014-01-01)

GM-CSF-Dependent Inflammatory Pathways
de réir: John A. Hamilton, et al.
Foilsithe / Cruthaithe: (2019-09-01)

GM-CSF Induces Cyclin D1 Expression and Proliferation of Endothelial Progenitor Cells via PI3K and MAPK Signaling
de réir: Chaolin Qiu, et al.
Foilsithe / Cruthaithe: (2014-03-01)

GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer
de réir: Xue Xiang, et al.
Foilsithe / Cruthaithe: (2022-05-01)

Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia
de réir: Shannon E. Gilchrist, et al.
Foilsithe / Cruthaithe: (2021-11-01)

GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis
de réir: Daisuke Tsukui, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Actin filament reorganization in HL-60 leukemia cell line after treatment with G-CSF and GM-CSF.
de réir: Anna Litwiniec, et al.
Foilsithe / Cruthaithe: (2007-10-01)

Response to treatment with TNFα inhibitors in rheumatoid arthritis is associated with high levels of GM-CSF and GM-CSF(+) T lymphocytes
de réir: Bystrom, J, et al.
Foilsithe / Cruthaithe: (2017)

Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity
de réir: Mariya Pykhtina, et al.
Foilsithe / Cruthaithe: (2021-05-01)

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract
de réir: Kate H. Gartlan, et al.
Foilsithe / Cruthaithe: (2019-10-01)

Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
de réir: Aoi Shiomi, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Role of GM-CSF in lung balance and disease
de réir: Yingzi Chen, et al.
Foilsithe / Cruthaithe: (2023-04-01)

M-CSF and GM-CSF determinate fibromodulatory activity of polarized human macrophages
de réir: A. A. Maksimova, et al.
Foilsithe / Cruthaithe: (2022-11-01)

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors
de réir: Kai He, et al.
Foilsithe / Cruthaithe: (2022-07-01)

Safety and efficacy of sargramostim (GM‐CSF) in the treatment of Alzheimer's disease
de réir: Huntington Potter, et al.
Foilsithe / Cruthaithe: (2021-01-01)

Generation and utilization of a HEK-293T murine GM-CSF expressing cell line.
de réir: Elektra Kantzari Robinson, et al.
Foilsithe / Cruthaithe: (2021-01-01)

GM-CSF: A Promising Target in Inflammation and Autoimmunity
de réir: Lee KMC, et al.
Foilsithe / Cruthaithe: (2020-10-01)

Functional characterization of GM-CSF induced monocyte subsets
de réir: Däbritz J, et al.
Foilsithe / Cruthaithe: (2008-09-01)

Research Upregulation of CD23 (FcεRII) Expression in Human Airway Smooth Muscle Cells (huASMC) in Response to IL-4, GM-CSF, and IL-4/GM-CSF
de réir: Lew D Betty, et al.
Foilsithe / Cruthaithe: (2005-05-01)

A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
de réir: Bursill, C, et al.
Foilsithe / Cruthaithe: (2005)

Characterization of the function and expression of the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor with a novel GM-CSF fusion protein
de réir: Rosas, M, et al.
Foilsithe / Cruthaithe: (2005)

Prolonged Survival of Neutrophils Induced by Tumor‐Derived G‐CSF/GM‐CSF Promotes Immunosuppression and Progression in Laryngeal Squamous Cell Carcinoma
de réir: Xiaoke Zhu, et al.
Foilsithe / Cruthaithe: (2024-12-01)

M-CSF and GM-CSF Regulation of STAT5 Activation and DNA Binding in Myeloid Cell Differentiation is Disrupted in Nonobese Diabetic Mice
de réir: B. Rumore-Maton, et al.
Foilsithe / Cruthaithe: (2008-01-01)

Leakage Performance of the GM + CCL Liner System for the MSW Landfill
de réir: Fan Jingjing
Foilsithe / Cruthaithe: (2014-01-01)

Synergism between Curdlan and GM-CSF confers a strong inflammatory signature to Dendritic cells
de réir: Min, Lin, et al.
Foilsithe / Cruthaithe: (2013)