CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.

CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.

The chemokine eotaxin/CCL11 is an important mediator of leukocyte migration, but its effect on inflammatory cytokine signaling has not been explored. In this study, we find that CCL11 induces suppressor of cytokine signaling (SOCS)1 and SOCS3 expression in murine macrophages, human monocytes, and de...

Podrobná bibliografie
Hlavní autoři:	Stevenson, N, Addley, MR, Ryan, E, Boyd, C, Carroll, H, Paunovic, V, Bursill, C, Miller, H, Channon, K, McClurg, A, Armstrong, M, Coulter, W, Greaves, D, Johnston, J
Médium:	Journal article
Jazyk:	English
Vydáno:	2009

Podobné jednotky

Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11.
Autor: Stevenson, N, a další
Vydáno: (2010)

JAK inhibitors impair GM-CSF-mediated signaling in innate immune cells
Autor: Yuya Fujita, a další
Vydáno: (2020-06-01)

Development of Dendritic Cells from GM-CSF-/-Mice invitro : GM-CSF Enhances Productionand Survival of Cells
Autor: Keping Ni, a další
Vydáno: (2001-01-01)

Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function
Autor: Eliana Ribechini, a další
Vydáno: (2017-06-01)

Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
Autor: Bryan D. Bryson, a další
Vydáno: (2019-05-01)

Suppressor of cytokine signalling protein SOCS3 expression is increased at sites of acute and chronic inflammation.
Autor: White, G, a další
Vydáno: (2011)

GM‐CSF signalling in Th17‐cell pathogenicity: The culprit in autoimmune uveitis promoted by sleep loss
Autor: Chun Zhang, a další
Vydáno: (2023-06-01)

Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders
Autor: Hillard M. Lazarus, a další
Vydáno: (2023-01-01)

Senescent cells promote breast cancer cells motility by secreting GM-CSF and bFGF that activate the JNK signaling pathway
Autor: Nan Wang, a další
Vydáno: (2024-10-01)

Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes
Autor: Ramon M. Rodriguez, a další
Vydáno: (2019-10-01)

GM-CSF Promotes the Expansion and Differentiation of Cord Blood Myeloid-Derived Suppressor Cells, Which Attenuate Xenogeneic Graft-vs.-Host Disease
Autor: Mi-Young Park, a další
Vydáno: (2019-02-01)

GM-CSF Monocyte-Derived Cells and Langerhans Cells As Part of the Dendritic Cell Family
Autor: Manfred B. Lutz, a další
Vydáno: (2017-10-01)

Immune Evasion of G-CSF and GM-CSF in Lung Cancer
Autor: Yeonhee Park, a další
Vydáno: (2024-01-01)

Gene Regulatory Network of Human GM-CSF-Secreting T Helper Cells
Autor: Szabolcs Éliás, a další
Vydáno: (2021-01-01)

Whole tumor cell vaccines engineered to secrete GM‐CSF (GVAX)
Autor: Robert J. Soiffer, a další
Vydáno: (2021-06-01)

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.
Autor: Alissa C Rothchild, a další
Vydáno: (2014-01-01)

GM-CSF-Dependent Inflammatory Pathways
Autor: John A. Hamilton, a další
Vydáno: (2019-09-01)

GM-CSF Induces Cyclin D1 Expression and Proliferation of Endothelial Progenitor Cells via PI3K and MAPK Signaling
Autor: Chaolin Qiu, a další
Vydáno: (2014-03-01)

GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer
Autor: Xue Xiang, a další
Vydáno: (2022-05-01)

Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia
Autor: Shannon E. Gilchrist, a další
Vydáno: (2021-11-01)

GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis
Autor: Daisuke Tsukui, a další
Vydáno: (2023-08-01)

Actin filament reorganization in HL-60 leukemia cell line after treatment with G-CSF and GM-CSF.
Autor: Anna Litwiniec, a další
Vydáno: (2007-10-01)

Response to treatment with TNFα inhibitors in rheumatoid arthritis is associated with high levels of GM-CSF and GM-CSF(+) T lymphocytes
Autor: Bystrom, J, a další
Vydáno: (2017)

Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity
Autor: Mariya Pykhtina, a další
Vydáno: (2021-05-01)

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract
Autor: Kate H. Gartlan, a další
Vydáno: (2019-10-01)

Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
Autor: Aoi Shiomi, a další
Vydáno: (2015-01-01)

Role of GM-CSF in lung balance and disease
Autor: Yingzi Chen, a další
Vydáno: (2023-04-01)

M-CSF and GM-CSF determinate fibromodulatory activity of polarized human macrophages
Autor: A. A. Maksimova, a další
Vydáno: (2022-11-01)

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors
Autor: Kai He, a další
Vydáno: (2022-07-01)

Safety and efficacy of sargramostim (GM‐CSF) in the treatment of Alzheimer's disease
Autor: Huntington Potter, a další
Vydáno: (2021-01-01)

Generation and utilization of a HEK-293T murine GM-CSF expressing cell line.
Autor: Elektra Kantzari Robinson, a další
Vydáno: (2021-01-01)

GM-CSF: A Promising Target in Inflammation and Autoimmunity
Autor: Lee KMC, a další
Vydáno: (2020-10-01)

Functional characterization of GM-CSF induced monocyte subsets
Autor: Däbritz J, a další
Vydáno: (2008-09-01)

Research Upregulation of CD23 (FcεRII) Expression in Human Airway Smooth Muscle Cells (huASMC) in Response to IL-4, GM-CSF, and IL-4/GM-CSF
Autor: Lew D Betty, a další
Vydáno: (2005-05-01)

A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
Autor: Bursill, C, a další
Vydáno: (2005)

Characterization of the function and expression of the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor with a novel GM-CSF fusion protein
Autor: Rosas, M, a další
Vydáno: (2005)

Prolonged Survival of Neutrophils Induced by Tumor‐Derived G‐CSF/GM‐CSF Promotes Immunosuppression and Progression in Laryngeal Squamous Cell Carcinoma
Autor: Xiaoke Zhu, a další
Vydáno: (2024-12-01)

M-CSF and GM-CSF Regulation of STAT5 Activation and DNA Binding in Myeloid Cell Differentiation is Disrupted in Nonobese Diabetic Mice
Autor: B. Rumore-Maton, a další
Vydáno: (2008-01-01)

Leakage Performance of the GM + CCL Liner System for the MSW Landfill
Autor: Fan Jingjing
Vydáno: (2014-01-01)

Synergism between Curdlan and GM-CSF confers a strong inflammatory signature to Dendritic cells
Autor: Min, Lin, a další
Vydáno: (2013)