Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD.

Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD.

PURPOSE: Exudative AMD (wet AMD) is treated by monthly injection into the eye of anti-VEGF proteins. VEGF is alternatively spliced to produce numerous isoforms that differ in angiogenic activity. Serine-rich protein kinase-1 (SRPK1) has been identified as a regulator of pro-angiogenic VEGF splicing...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Gammons, M, Fedorov, O, Ivison, D, Du, C, Clark, T, Hopkins, C, Hagiwara, M, Dick, A, Cox, R, Harper, S, Hancox, J, Knapp, S, Bates, DO
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2013

অনুরূপ উপাদানগুলি

অনুরূপ উপাদানগুলি