Comparing Pooled Peptides with Intact Protein for Accessing Cross-presentation Pathways for Protective CD8+ and CD4+ T Cells

Comparing Pooled Peptides with Intact Protein for Accessing Cross-presentation Pathways for Protective CD8+ and CD4+ T Cells

To better understand the mechanisms of intracellular trafficking and presentation of exogenous peptides by antigen-presenting cells (APC), we compared the handling of overlapping 24-mer peptides from HIV Nef either mixed or covalently linked in tandem in one protein. Once internalized, peptides traf...

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Bibliographic Details
Main Authors:	Zhang, H, Hong, H, Li, D, Ma, S, Di, Y, Stoten, A, Haig, N, Di Gleria, K, Yu, Z, Xu, X, McMichael, A, Jiang, S
Format:	Journal article
Language:	English
Published:	American Society for Biochemistry & Molecular Biology 2009

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