Comparing Pooled Peptides with Intact Protein for Accessing Cross-presentation Pathways for Protective CD8+ and CD4+ T Cells
To better understand the mechanisms of intracellular trafficking and presentation of exogenous peptides by antigen-presenting cells (APC), we compared the handling of overlapping 24-mer peptides from HIV Nef either mixed or covalently linked in tandem in one protein. Once internalized, peptides traf...
Hlavní autoři: | , , , , , , , , , , , |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
American Society for Biochemistry & Molecular Biology
2009
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