Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer.

Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer.

PURPOSE: This randomized, open-label trial compared dacomitinib (PF-00299804), an irreversible inhibitor of human epidermal growth factor receptors (EGFR)/HER1, HER2, and HER4, with erlotinib, a reversible EGFR inhibitor, in patients with advanced non-small-cell lung cancer (NSCLC). PATIENTS AND ME...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ramalingam, S, Blackhall, F, Krzakowski, M, Barrios, C, Park, K, Bover, I, Seog Heo, D, Rosell, R, Talbot, D, Frank, R, Letrent, S, Ruiz-Garcia, A, Taylor, I, Liang, J, Campbell, A, O'Connell, J, Boyer, M
Format: Journal article
Sprache:English
Veröffentlicht: 2012

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