Understanding the genetic relationship between key effectors of DNA interstrand crosslink repair
<p>With each cell division, our whole genome is duplicated in an error-free and controlled manner. Failure to do so leads to genomic instability. DNA interstrand crosslinks (ICLs) are particularly toxic DNA lesions as when left unrepaired, they are able to block replication producing devastati...
المؤلف الرئيسي: | Brolih, S |
---|---|
مؤلفون آخرون: | McHugh, P |
التنسيق: | أطروحة |
منشور في: |
2016
|
مواد مشابهة
-
The role of PARPs and APLF in DNA interstrand crosslink repair
حسب: Zobel, F
منشور في: (2017) -
The role of ADP-ribosylation in regulating DNA interstrand crosslink repair
حسب: Gunn, A, وآخرون
منشور في: (2016) -
WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair
حسب: Socha, A, وآخرون
منشور في: (2020) -
Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway
حسب: Niyo Kato, وآخرون
منشور في: (2017-10-01) -
RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.
حسب: Abdullah, U, وآخرون
منشور في: (2017)