Understanding the genetic relationship between key effectors of DNA interstrand crosslink repair

Understanding the genetic relationship between key effectors of DNA interstrand crosslink repair

<p>With each cell division, our whole genome is duplicated in an error-free and controlled manner. Failure to do so leads to genomic instability. DNA interstrand crosslinks (ICLs) are particularly toxic DNA lesions as when left unrepaired, they are able to block replication producing devastati...

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Bibliografiske detaljer
Hovedforfatter:	Brolih, S
Andre forfattere:	McHugh, P
Format:	Thesis
Udgivet:	2016

Lignende værker

The role of PARPs and APLF in DNA interstrand crosslink repair
af: Zobel, F
Udgivet: (2017)

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair
af: Gunn, A, et al.
Udgivet: (2016)

WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair
af: Socha, A, et al.
Udgivet: (2020)

RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.
af: Abdullah, U, et al.
Udgivet: (2017)

RPA activates the XPF‐ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks
af: Abdullah, U, et al.
Udgivet: (2017)

Targeting interstrand crosslink repair to improve chemotherapeutic strategies
af: Castle, L
Udgivet: (2017)

UHRF1 is a sensor for DNA interstrand crosslinks.
af: Cohn, M, et al.
Udgivet: (2016)

Replication fork reversal during DNA interstrand crosslink repair requires CMG unloading
af: Amunugama, R, et al.
Udgivet: (2018)

DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta.
af: Sarkar, S, et al.
Udgivet: (2006)

Identification of novel players implicated in replication-dependent and independent DNA interstrand crosslink (ICL) repair
af: Yaprianto, K
Udgivet: (2021)

Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway
af: Lopez-Martinez, D, et al.
Udgivet: (2016)

CtIP is required to initiate replication-dependent interstrand crosslink repair.
af: Michelle L Duquette, et al.
Udgivet: (2012-01-01)

Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast
af: Ward, T, et al.
Udgivet: (2012)

Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.
af: Thomas A Ward, et al.
Udgivet: (2012-01-01)

Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein
af: Motnenko, A, et al.
Udgivet: (2018)

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.
af: Iyama, T, et al.
Udgivet: (2015)

DNA interstrand cross-link repair in Saccharomyces cerevisiae.
af: Lehoczký, P, et al.
Udgivet: (2007)

The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks prior to monoubiquitination of FANCD2
af: Liang, C, et al.
Udgivet: (2016)

Visualizing Inhibition of Nucleosome Mobility and Transcription by Cisplatin-DNA Interstrand Crosslinks in Live Mammalian Cells
af: Zhu, Guangyu, et al.
Udgivet: (2014)

Interstrand crosslinking oligonucleotides elucidate the effect of metal ions on the methylation status of repetitive DNA elements
af: Shan Liu, et al.
Udgivet: (2023-01-01)

Dual targeting of <i>Saccharomyces cerevisiae</i> Pso2 to mitochondria and the nucleus, and its functional relevance in the repair of DNA interstrand crosslinks
af: Shravanahalli C Somashekara, et al.
Udgivet: (2022-04-01)

Human MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repair.
af: Qi Wu, et al.
Udgivet: (2008-09-01)

Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.
af: Sengerová, B, et al.
Udgivet: (2011)

DNA interstrand cross-link repair requires replication-fork convergence
af: Zhang, J, et al.
Udgivet: (2015)

The analysis of DNA interstrand cross-links and their repair by the modified comet assay
af: Castle, L, et al.
Udgivet: (2020)

DNA interstrand cross-link repair requires replication-fork convergence
af: Zhang, J, et al.
Udgivet: (2015)

C. elegans ring finger protein RNF-113 is involved in interstrand DNA crosslink repair and interacts with a RAD51C homolog.
af: Hyojin Lee, et al.
Udgivet: (2013-01-01)

ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.
af: Bianca M Sirbu, et al.
Udgivet: (2011-01-01)

Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repair.
af: Kelly Beagan, et al.
Udgivet: (2017-05-01)

Preparation of DNA interstrand cross-link repair intermediates induced by abasic sites
af: Jin Tang, et al.
Udgivet: (2022-01-01)

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression
af: Kaina Bernd, et al.
Udgivet: (2010-09-01)

UHRF1 Is a sensor for DNA interstrand crosslinks and recruits FANCD2 to initiate the Fanconi Anemia pathway
af: Liang, C, et al.
Udgivet: (2015)

UHRF1 Is a Sensor for DNA Interstrand Crosslinks and Recruits FANCD2 to Initiate the Fanconi Anemia Pathway
af: Chih-Chao Liang, et al.
Udgivet: (2015-03-01)

DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.
af: Wai Shan Yuen, et al.
Udgivet: (2012-01-01)

Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2
af: Jing Huang, et al.
Udgivet: (2019-05-01)

Elevated levels of STAT1 in Fanconi anemia group A lymphoblasts correlate with the cells’ sensitivity to DNA interstrand crosslinking drugs
af: Inés Prieto-Remón, et al.
Udgivet: (2013-05-01)

Replication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts.
af: Cyrille Le Breton, et al.
Udgivet: (2011-04-01)

Genetic inactivation of the Fanconi anemia gene <it>FANCC </it>identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand crosslinking agents
af: Bassermann Florian, et al.
Udgivet: (2010-05-01)

Chronometric Administration of Cyclophosphamide and a Double-Stranded DNA-Mix at Interstrand Crosslinks Repair Timing, Called “Karanahan” Therapy, Is Highly Efficient in a Weakly Immunogenic Lewis Carcinoma Model
af: Vera Ruzanova, et al.
Udgivet: (2022-05-01)

Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links.
af: Lambert, S, et al.
Udgivet: (2003)