Understanding the genetic relationship between key effectors of DNA interstrand crosslink repair
<p>With each cell division, our whole genome is duplicated in an error-free and controlled manner. Failure to do so leads to genomic instability. DNA interstrand crosslinks (ICLs) are particularly toxic DNA lesions as when left unrepaired, they are able to block replication producing devastati...
Κύριος συγγραφέας: | Brolih, S |
---|---|
Άλλοι συγγραφείς: | McHugh, P |
Μορφή: | Thesis |
Έκδοση: |
2016
|
Παρόμοια τεκμήρια
-
The role of PARPs and APLF in DNA interstrand crosslink repair
ανά: Zobel, F
Έκδοση: (2017) -
The role of ADP-ribosylation in regulating DNA interstrand crosslink repair
ανά: Gunn, A, κ.ά.
Έκδοση: (2016) -
WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair
ανά: Socha, A, κ.ά.
Έκδοση: (2020) -
Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway
ανά: Niyo Kato, κ.ά.
Έκδοση: (2017-10-01) -
RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.
ανά: Abdullah, U, κ.ά.
Έκδοση: (2017)