Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis.

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis.

IL-1 is an important mediator of inflammation and a major cause of tissue damage in rheumatoid arthritis (RA). Therapeutic administration of recombinant IL-1 receptor antagonist (IL-1Ra) is efficacious in reducing clinical symptoms of disease, but suffers from several drawbacks, including the need f...

Podrobná bibliografie
Hlavní autoři:	Spohn, G, Keller, I, Beck, M, Grest, P, Jennings, G, Bachmann, M
Médium:	Journal article
Jazyk:	English
Vydáno:	2008

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