Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis.
IL-1 is an important mediator of inflammation and a major cause of tissue damage in rheumatoid arthritis (RA). Therapeutic administration of recombinant IL-1 receptor antagonist (IL-1Ra) is efficacious in reducing clinical symptoms of disease, but suffers from several drawbacks, including the need f...
Үндсэн зохиолчид: | Spohn, G, Keller, I, Beck, M, Grest, P, Jennings, G, Bachmann, M |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2008
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