Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold.
A supramolecular assembly containing an isoguanosine pentaplex with both a "protein-binding" face and a "reporter" face has been generated. When phosphocholine is appended to the protein-binding face this supramolecular assembly binds multivalently to the pentameric human C-react...
প্রধান লেখক: | , , , , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2009
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_version_ | 1826279180144214016 |
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author | Rosenzweig, B Ross, N Tagore, D Jayawickramarajah, J Saraogi, I Hamilton, A |
author_facet | Rosenzweig, B Ross, N Tagore, D Jayawickramarajah, J Saraogi, I Hamilton, A |
author_sort | Rosenzweig, B |
collection | OXFORD |
description | A supramolecular assembly containing an isoguanosine pentaplex with both a "protein-binding" face and a "reporter" face has been generated. When phosphocholine is appended to the protein-binding face this supramolecular assembly binds multivalently to the pentameric human C-reactive protein, a biomolecule implicated in inflammation and heart disease. |
first_indexed | 2024-03-06T23:54:55Z |
format | Journal article |
id | oxford-uuid:73e208b4-eb28-4e79-bb99-8b0b08b117e6 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T23:54:55Z |
publishDate | 2009 |
record_format | dspace |
spelling | oxford-uuid:73e208b4-eb28-4e79-bb99-8b0b08b117e62022-03-26T19:59:12ZMultivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:73e208b4-eb28-4e79-bb99-8b0b08b117e6EnglishSymplectic Elements at Oxford2009Rosenzweig, BRoss, NTagore, DJayawickramarajah, JSaraogi, IHamilton, AA supramolecular assembly containing an isoguanosine pentaplex with both a "protein-binding" face and a "reporter" face has been generated. When phosphocholine is appended to the protein-binding face this supramolecular assembly binds multivalently to the pentameric human C-reactive protein, a biomolecule implicated in inflammation and heart disease. |
spellingShingle | Rosenzweig, B Ross, N Tagore, D Jayawickramarajah, J Saraogi, I Hamilton, A Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold. |
title | Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold. |
title_full | Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold. |
title_fullStr | Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold. |
title_full_unstemmed | Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold. |
title_short | Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold. |
title_sort | multivalent protein binding and precipitation by self assembling molecules on a dna pentaplex scaffold |
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