Plasmodium vivax trophozoites insensitive to chloroquine.
BACKGROUND: Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium spp. trophozoite, the stage when haemoglobin ca...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
BioMed Central
2008
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