Plasmodium vivax trophozoites insensitive to chloroquine.

BACKGROUND: Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium spp. trophozoite, the stage when haemoglobin ca...

Descripció completa

Dades bibliogràfiques
Autors principals: Sharrock, W, Suwanarusk, R, Lek-Uthai, U, Edstein, MD, Kosaisavee, V, Travers, T, Jaidee, A, Sriprawat, K, Price, R, Nosten, F, Russell, B
Format: Journal article
Idioma:English
Publicat: BioMed Central 2008

Ítems similars