Human epicardial adipose tissue-secreted miR-92a-3p regulates myocardial redox state via paracrine signalling: implications for cardiovascular clinical outcomes

Human epicardial adipose tissue-secreted miR-92a-3p regulates myocardial redox state via paracrine signalling: implications for cardiovascular clinical outcomes

Bibliografiske detaljer
Main Authors:	Badi, I, Carena, MC, Polkinghorne, M, Akoumianakis, I, Douglas, G, Kotanidis, CP, Akawi, N, Antonopoulos, AS, Psarros, C, Sayeed, R, Krasopoulos, G, Srivastava, V, Channon, KM, Casadei, B, Antoniades, C
Format:	Journal article
Sprog:	English
Udgivet:	Oxford University Press 2023

Lignende værker

Role of human epicardial adipose tissue–derived miR-92a-3p in myocardial redox state
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A human arterial transcriptomic signature predicts major adverse cardiac events and identifies novel, redox-related therapeutic targets within the vascular wall
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af: Kondo, H, et al.
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Myocardial redox state predicts 3-year mortality in patients undergoing cardiac surgery: the ox-HVF study
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Udgivet: (2019)

Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-γ/Adiponectin Signalling
af: Antonopoulos, A, et al.
Udgivet: (2016)

A novel human arterial transcriptomic signature associated with major adverse cardiovascular events and oxidative stress
af: Kotanidis, C, et al.
Udgivet: (2021)

A novel arterial redox-specific machine learning-derived radiomic signature of perivascular adipose tissue predicts cardiac mortality from routine CCTA
af: Kotanidis, CP, et al.
Udgivet: (2020)

Oxidative stress in the myocardium as a novel predictor of long-term outcomes in patients undergoing cardiac surgery
af: Kotanidis, CP, et al.
Udgivet: (2019)

A Novel Cross-Talk Between Epicardial Adipose Tissue and the Human Heart Regulates Myocardial Redox State in Ischaemic Heart Disease
af: Antonopoulos, A, et al.
Udgivet: (2013)

Novel direct effects of SGLT2 inhibitor, Canagliflozin, on myocardial redox state in humans
af: Kondo, H, et al.
Udgivet: (2019)

Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition
af: Akoumianakis, I, et al.
Udgivet: (2020)

Fat-secreted ceramides regulate vascular redox state and influence outcomes in patients with cardiovascular disease
af: Akawi, N, et al.
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Abstract 15072: Lipoprotein(a) regulates vascular redox state and predicts adverse cardiovascular outcomes in coronary artery disease
af: Polkinghorne, MD, et al.
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Genetic variability of lipoprotein(a) controls vascular inflammation/redox signalling and predicts adverse cardiovascular outcomes in coronary artery disease
af: Polkinghorne, MD, et al.
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NADPH oxidase activity in internal mammary arteries predicts mortality in patients undergoing coronary bypass surgery
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Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17//RAC1-mediated activation of NADPH oxidases
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Udgivet: (2019)

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Perivascular adipose tissue-derived Wnt5a as a regulator of human vascular disease pathogenesis
af: Akoumianakis, I, et al.
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Udgivet: (2017)

Impaired vascular redox signalling in the vascular complications of obesity and diabetes mellitus
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The role of epicardial fat in pericardial diseases
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Epicardial Fat, Paracrine-mediated Inflammation and Atrial Fibrillation
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Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications
af: Akoumianakis, I, et al.
Udgivet: (2022)

The role of epicardial adipose tissue in cardiac biology: classic concepts and emerging roles
af: Antonopoulos, A, et al.
Udgivet: (2017)

Cardiac magnetic resonance imaging of epicardial and intramyocardial adiposity as an early sign of myocardial disease
af: Antonopoulos, A, et al.
Udgivet: (2018)

Predictive value of telomere length on outcome following acute myocardial infarction: Evidence for contrasting effects of vascular vs. blood oxidative stress
af: Margaritis, M, et al.
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Insulin triggers oxidative stress in the vascular wall of patients with atherosclerosis, independently of systemic insulin resistance: the beneficial role of DPP-IV inhibition
af: Akoumianakis, I, et al.
Udgivet: (2018)

Insulin Treatment Induces Oxidative Stress in the Vascular Wall of Patients With Atherosclerosis Independently of Diabetes or Systemic Insulin Resistance: The Protective Role of DPP-IV Inhibition
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Udgivet: (2018)

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af: Akoumianakis, I, et al.
Udgivet: (2018)

Targeting redox signaling in the vascular wall: from basic science to clinical practice.
af: Antoniades, C, et al.
Udgivet: (2009)

Novel therapeutic strategies targeting vascular redox in human atherosclerosis.
af: Antonopoulos, A, et al.
Udgivet: (2009)

Atorvastatin rapidly improves redox state in human vein grafts ex-vivo, by directly reducing NADPH-oxidase activity and improving eNOS coupling
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Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia
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The role of adiponectin at different stages of atherosclerosis in heart failure: associations with myocardial redox state
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Udgivet: (2010)

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Udgivet: (2016)

Echocardiographic pre-operative early mitral inflow velocity-to-early diastolic strain rate ratio predicts post-operative paroxysmal atrial fibrillation in patients undergoing CABG surgery
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Systemic and local myocardial redox state as predictors of post-operative outcome in patients undergoing coronary artery bypass grafting
af: Margaritis, M, et al.
Udgivet: (2011)