A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer.

A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer.

Our objective was to compare 111In-labeled human epidermal growth factor (hEGF), a 53-amino acid peptide with anti-epidermal growth factor receptor (EGFR) monoclonal antibody (MAb) 528 (IgG2a) for imaging EGFR-positive breast cancer. METHODS: hEGF and MAb 528 were derivatized with diethylenetriamine...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Reilly, R, Kiarash, R, Sandhu, J, Lee, Y, Cameron, R, Hendler, A, Vallis, K, Gariépy, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2000

Eitemau Tebyg

111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR.
gan: Reilly, R, et al.
Cyhoeddwyd: (2000)

In-111-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR
gan: Reilly, R, et al.
Cyhoeddwyd: (2000)

Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells.
gan: Chen, P, et al.
Cyhoeddwyd: (2002)

The anti-tumor effect of the auger electron-emitting radiopharmaceutical, In-111-hEGF against MDA-MB-468 human breast cancer xenografts is tumor-size dependent.
gan: Chen, P, et al.
Cyhoeddwyd: (2001)

Amplified delivery of indium-111 to EGFR-positive human breast cancer cells.
gan: Wang, J, et al.
Cyhoeddwyd: (2001)

Relationship between induction of phosphorylated H2AX and survival in breast cancer cells exposed to 111In-DTPA-hEGF.
gan: Cai, Z, et al.
Cyhoeddwyd: (2008)

Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software.
gan: Cai, Z, et al.
Cyhoeddwyd: (2009)

Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cytotoxicity, and tumor and normal-tissue uptake of [111In]DTPA-hEGF.
gan: Hu, M, et al.
Cyhoeddwyd: (2007)

Accumulation of 111In-Labelled EGF-Au-PEG Nanoparticles in EGFR-Positive Tumours is Enhanced by Co-administration of Targeting Ligand
gan: Song, L, et al.
Cyhoeddwyd: (2017)

SPECT imaging and biodistribution studies of 111In-EGF-Au-PEG nanoparticles in vivo
gan: Song, L, et al.
Cyhoeddwyd: (2016)

Antitumor effects and normal tissue toxicity of 111In-labeled epidermal growth factor administered to athymic mice bearing epidermal growth factor receptor-positive human breast cancer xenografts.
gan: Chen, P, et al.
Cyhoeddwyd: (2003)

A phase I study of Tc-99m-h-R3 monoclonal antibody (DiaCIM (R)), a humanized monoclonal antibody (mAB) for imaging EGFR-positive malignancies.
gan: Reilly, R, et al.
Cyhoeddwyd: (2002)

A phase I clinical trial to evaluate the pharmacokinetics, toxicity and dosimetry of 111-indium-labeled human epidermal growth factor in patients with metastatic breast cancer
gan: Vallis, K, et al.
Cyhoeddwyd: (2005)

(111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer.
gan: Costantini, D, et al.
Cyhoeddwyd: (2007)

Indium-111 labeled anti-CD33 monoclonal antibodies (mAbs) modified with nuclear-localizing sequences (NLS) kill mitoxantrone-resistant HL-60 acute myelogenous leukemia (AML) cells
gan: Kersemans, V, et al.
Cyhoeddwyd: (2006)

Antitumor Effect of MAb EMD 55900 Depends on EGF-R Expression and Histopathology
gan: Christine Solbach, et al.
Cyhoeddwyd: (2002-01-01)

Preclinical pharmacokinetic, biodistribution, toxicology, and dosimetry studies of 111In-DTPA-human epidermal growth factor: an auger electron-emitting radiotherapeutic agent for epidermal growth factor receptor-positive breast cancer.
gan: Reilly, R, et al.
Cyhoeddwyd: (2006)

Antisense imaging of epidermal growth factor (EGF) induced p21(WAF-1/CIP-1) mRNA in MDA-MB-468 human breast cancer xenografts.
gan: Wang, J, et al.
Cyhoeddwyd: (2002)

ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy.
gan: Cornelissen, B, et al.
Cyhoeddwyd: (2011)

A kit formulated under good manufacturing practices for labeling human epidermal growth factor with 111In for radiotherapeutic applications.
gan: Reilly, R, et al.
Cyhoeddwyd: (2004)

Preoperative Localization of a Gastrin-Secreting Tumour by Total Body Imaging with 111Indium-Labelled Pentatreotide
gan: Humera Ali, et al.
Cyhoeddwyd: (1994-01-01)

Methotrexate, paclitaxel, and doxorubicin radiosensitize HER2-amplified human breast cancer cells to the Auger electron-emitting radiotherapeutic agent (111)In-NLS-trastuzumab.
gan: Costantini, D, et al.
Cyhoeddwyd: (2010)

Auger electron therapy using In-111-labelled F3 peptide
gan: Cornelissen, B, et al.
Cyhoeddwyd: (2011)

Trastuzumab-resistant breast cancer cells remain sensitive to the auger electron-emitting radiotherapeutic agent 111In-NLS-trastuzumab and are radiosensitized by methotrexate.
gan: Costantini, D, et al.
Cyhoeddwyd: (2008)

Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation
gan: Owen, J, et al.
Cyhoeddwyd: (2019)

Antitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts.
gan: Costantini, D, et al.
Cyhoeddwyd: (2010)

A phase I trial of In-111-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer
gan: Vallis, K, et al.
Cyhoeddwyd: (2008)

Cellular penetration and nuclear importation properties of 111In-labeled and 123I-labeled HIV-1 tat peptide immunoconjugates in BT-474 human breast cancer cells.
gan: Cornelissen, B, et al.
Cyhoeddwyd: (2007)

UMP terima 1,528 pelajar baharu
gan: Nik Amirulmu'min, Nik Min
Cyhoeddwyd: (2021)

111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells
gan: Gill, M, et al.
Cyhoeddwyd: (2018)

P5.28 GESTATIONAL HYPERTENSION – AN OVERLOOKED INDICATOR FOR FUTURE CARDIOVASCULAR RISK
gan: K.L. Miles, et al.
Cyhoeddwyd: (2011-11-01)

1,528 new students are now part of UMP family
gan: Mimi Rabita, Abdul Wahit
Cyhoeddwyd: (2021)

Kinetics of internalization and nuclear import and efflux of 111In-and 123I-labeled HIV-1 tat-peptide immunoconjugates (IC's) in BT-474 human breast cancer cells
gan: Cornelissen, B, et al.
Cyhoeddwyd: (2006)

MAB Regeerprogram “avant la lettre” MAB
gan: F. Hartog
Cyhoeddwyd: (1994-07-01)

Properties of [(111)In]-labeled HIV-1 tat peptide radioimmunoconjugates in tumor-bearing mice following intravenous or intratumoral injection.
gan: Cornelissen, B, et al.
Cyhoeddwyd: (2008)

CCS528 – Information Security and Cryptography (Keselamatan Maklumat dan Kriptografi)
gan: PPSKOM, Pusat Pengajian Sains Komputer
Cyhoeddwyd: (2023)

1,528 pelajar baharu kini merupakan sebahagian keluarga UMP
gan: Mimi Rabita, Abdul Wahit
Cyhoeddwyd: (2021)

An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells
gan: Gill, MR, et al.
Cyhoeddwyd: (2020)

Influence of macrocyclic chelators on the targeting properties of (68)Ga-labeled synthetic affibody molecules: comparison with (111)In-labeled counterparts.
gan: Joanna Strand, et al.
Cyhoeddwyd: (2013-01-01)

EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.
gan: Song, L, et al.
Cyhoeddwyd: (2016)