Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms.

Penicillin-binding protein 3 (PBP3) from Pseudomonas aeruginosa is the molecular target of β-lactam-based antibiotics. Structures of PBP3 in complexes with azlocillin and cefoperazone, which are in clinical use for the treatment of pseudomonad infections, have been determined to 2.0 Å resolution. To...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Ren, J, Nettleship, J, Males, A, Stuart, D, Owens, R
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Wiley 2016