Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.

Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.

A recent genome-wide association study by the International Multiple Sclerosis Genetics Consortium (IMSGC) reported association of 17 single-nucleotide polymorphisms (SNPs) in 14 loci with multiple sclerosis (MS). Only two loci, HLA-DRA and IL2RA, reached genome-wide significance (P<5E-08). I...

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Detalhes bibliográficos
Main Authors:	Hoppenbrouwers, I, Aulchenko, Y, Janssens, A, Ramagopalan, S, Broer, L, Kayser, M, Ebers, G, Oostra, B, van Duijn, C, Hintzen, R
Formato:	Journal article
Idioma:	English
Publicado em:	2009

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