Immunogenicity in mice of tandem repeats of an epitope from herpes simplex gD protein when expressed by recombinant adenovirus vectors.
The antigenic and immunogenic potential was examined of human adenovirus type 5 (Ad) recombinants carrying and expressing from one to four tandem repeats of a linear neutralizing epitope from the gD protein of herpes simplex virus type 1 (HSV-1) as a fusion with the beta-galactosidase protein. The f...
Main Authors: | Zheng, B, Graham, F, Johnson, D, Hanke, T, McDermott, MR, Prevec, L |
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Format: | Journal article |
Language: | English |
Published: |
1993
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