HLA*LA—HLA typing from linearly projected graph alignments

<p><strong>Summary</strong></p> <p>HLA*LA implements a new graph alignment model for human leukocyte antigen (HLA) type inference, based on the projection of linear alignments onto a variation graph. It enables accurate HLA type inference from whole-genome (99% accuracy...

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Detalhes bibliográficos
Main Authors: Dilthey, AT, Mentzer, AJ, Carapito, R, Cutland, C, Cereb, N, Madhi, SA, Rhie, A, Koren, S, Bahram, S, McVean, G, Phillippy, AM
Formato: Journal article
Idioma:English
Publicado em: Oxford University Press 2019