Structural basis for amino acid transport by the CAT family of SLC7 transporters

Amino acids play essential roles in cell biology as regulators of metabolic pathways. Arginine in particular is a major signalling molecule inside the cell, being a precursor for both l-ornithine and nitric oxide (NO) synthesis and a key regulator of the mTORC1 pathway. In mammals, cellular arginine...

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Bibliographic Details
Main Authors: Jungnickel, K, Parker, J, Newstead, S
Format: Journal article
Language:English
Published: Nature Publishing Group 2018

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