Structural basis for amino acid transport by the CAT family of SLC7 transporters
Amino acids play essential roles in cell biology as regulators of metabolic pathways. Arginine in particular is a major signalling molecule inside the cell, being a precursor for both l-ornithine and nitric oxide (NO) synthesis and a key regulator of the mTORC1 pathway. In mammals, cellular arginine...
Main Authors: | Jungnickel, K, Parker, J, Newstead, S |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2018
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