A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977
A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 is described using as the key step a stereoselective anomeric oxygen to carbon rearrangement of an alkynyl stannane tetrahydrofuranyl ether derivative mediated by boron trifluoride etherate.
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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| _version_ | 1797075946125131776 |
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| author | Dixon, D Ley, S Reynolds, D Chorghade, MS |
| author_facet | Dixon, D Ley, S Reynolds, D Chorghade, MS |
| author_sort | Dixon, D |
| collection | OXFORD |
| description | A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 is described using as the key step a stereoselective anomeric oxygen to carbon rearrangement of an alkynyl stannane tetrahydrofuranyl ether derivative mediated by boron trifluoride etherate. |
| first_indexed | 2024-03-06T23:57:24Z |
| format | Journal article |
| id | oxford-uuid:74b67d71-2ba4-4e72-bb81-a177016f43a7 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:57:24Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:74b67d71-2ba4-4e72-bb81-a177016f43a72022-03-26T20:04:44ZA short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:74b67d71-2ba4-4e72-bb81-a177016f43a7EnglishSymplectic Elements at Oxford2001Dixon, DLey, SReynolds, DChorghade, MSA short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 is described using as the key step a stereoselective anomeric oxygen to carbon rearrangement of an alkynyl stannane tetrahydrofuranyl ether derivative mediated by boron trifluoride etherate. |
| spellingShingle | Dixon, D Ley, S Reynolds, D Chorghade, MS A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
| title | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
| title_full | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
| title_fullStr | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
| title_full_unstemmed | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
| title_short | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
| title_sort | short and efficient stereoselective synthesis of the potent 5 lipoxygenase inhibitor cmi 977 |
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