A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

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A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 is described using as the key step a stereoselective anomeric oxygen to carbon rearrangement of an alkynyl stannane tetrahydrofuranyl ether derivative mediated by boron trifluoride etherate.

Manylion Llyfryddiaeth
Prif Awduron:	Dixon, D, Ley, S, Reynolds, D, Chorghade, MS
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2001

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