A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

Pokaži ostale verzije (2)

A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 is described using as the key step a stereoselective anomeric oxygen to carbon rearrangement of an alkynyl stannane tetrahydrofuranyl ether derivative mediated by boron trifluoride etherate.

Bibliografski detalji
Glavni autori:	Dixon, D, Ley, S, Reynolds, D, Chorghade, MS
Format:	Journal article
Jezik:	English
Izdano:	2001

Slični predmeti

A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977
od: Dixon, D, i dr.
Izdano: (2001)

A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor CMI-977
od: Dixon, D, i dr.
Izdano: (2000)

A short and efficient stereoselective synthesis of the polyhydroxylated macrolactone (+)-aspicillin
od: Dixon, D, i dr.
Izdano: (2000)

A short stereoselective total synthesis of the fusarium toxin equisetin.
od: Burke, LT, i dr.
Izdano: (2000)

A short stereoselective synthesis of (R)-salmeterol
od: Buchanan, D, i dr.
Izdano: (2005)

Inhibitors of Human 5-Lipoxygenase Potently Interfere With Prostaglandin Transport
od: Astrid S. Kahnt, i dr.
Izdano: (2022-01-01)

Biological evaluation of potent antioxidant, lipoxygenase inhibitor and antibacterial: A comparative study
od: Muhammad Aslam, i dr.
Izdano: (2016-01-01)

Butane-2,3-diacetal-desymmetrized glycolic acid—a new building block for the stereoselective synthesis of enantiopure α-hydroxy acids
od: Díez, E, i dr.
Izdano: (2001)

ON THE DATE OF THE OLBIAN CALENDAR GRAFFITO SEG 30: 977
od: Sofia Andreeva
Izdano: (2022-01-01)

A 2,3-butanedione protected chiral glycine equivalent - A new building block for the stereoselective synthesis of enantiopure N-protected α-amino acids
od: Dixon, D, i dr.
Izdano: (2003)

A 2,3-butanedione protected chiral glycine equivalent--a new building block for the stereoselective synthesis of enantiopure N-protected alpha-amino acids.
od: Dixon, D, i dr.
Izdano: (2003)

Investigating the effects of two novel 4-MMPB analogs as potent lipoxygenase inhibitors for prostate cancer treatment
od: Sonia Iranpour, i dr.
Izdano: (2021-05-01)

A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2.
od: J Brian Jameson, i dr.
Izdano: (2014-01-01)

Stereoselective Synthesis of Homofarnesenes: Establishment of an Efficient Method for the Stereoselective Preparation of Acyclic Tetrasubstituted Olefins
od: Wenhao Yin, i dr.
Izdano: (2018-04-01)

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors
od: Manu T. Kalathottukaren, i dr.
Izdano: (2018-08-01)

Total synthesis of thapsigargin, a potent SERCA pump inhibitor.
od: Ball, M, i dr.
Izdano: (2007)

Stereoselective spirolactam synthesis via palladium catalyzed arylative allene carbocyclization cascades.
od: Li, M, i dr.
Izdano: (2010)

CMI码功率谱
od: 王建利
Izdano: (1986-01-01)

Quadragésimo ano do parecer CFE nº 977/65
od: Carlos Roberto Jamil Cury
Izdano: (2005-01-01)

Design and synthesis of new esters of terpenoid alcohols as 15-lipoxygenase inhibitors
od: Hamid Sadeghian, i dr.
Izdano: (2018-07-01)

Catalytic stereoselective total synthesis of a spiro-oxindole alkaloid and the pentacyclic core of tryptoquivalines
od: Wei, T, i dr.
Izdano: (2018)

Nitro-Mannich/lactamization cascades for the direct stereoselective synthesis of pyrrolidin-2-ones.
od: Pelletier, S, i dr.
Izdano: (2009)

An efficient stereoselective total synthesis of 11β-methoxycurvularin
od: J. S. Yadav, i dr.
Izdano: (2014-08-01)

Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase
od: Yu Zhou, i dr.
Izdano: (2016-01-01)

Stereoselective synthesis of (-)-tetrahydropyrenophorol
od: Ramanujan Vyasabhattar, i dr.
Izdano: (2020-01-01)

Stereoselective synthesis of (-)-pestalotin
od: A. Shashidhar Kumar, i dr.
Izdano: (2004-11-01)

L23N F260 977-80) [fotograf udara]

Akta EKSAIS l976 : Peraturan-Peraturan Eksais l977.

P977: THE VENOUS THROMBOEMBOLISM RISK ASSESMENT MODELS IN MULTIPLE MYELOMA
od: Tugcan Alp Kirkizlar, i dr.
Izdano: (2023-08-01)

Parecer CFE no 977/65, aprovado em 3 dez. 1965
Izdano: (2005-01-01)

Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors
od: Mina Mousavian, i dr.
Izdano: (2020-08-01)

Effect of the Lipoxygenase Inhibitor Baicalein on Muscles in Ovariectomized Rats
od: D. Saul, i dr.
Izdano: (2016-01-01)

CMI embraces Open Access philosophy
od: Laura Fascio Pecetto
Izdano: (2013-03-01)

CMI between New York and Genoa
od: Giorgio Berlingieri
Izdano: (2018-02-01)

A stereoselective total synthesis of (±)-tormesol
od: Kim, H, i dr.
Izdano: (2011)

A stereoselective total synthesis of (±)-tormesol
od: Kim, H, i dr.
Izdano: (2011)

The total synthesis of the annonaceous acetogenin, muricatetrocin C.
od: Dixon, D, i dr.
Izdano: (2002)

The total synthesis of the annonaceous acetogenin, muricatetrocin C.
od: Dixon, D, i dr.
Izdano: (2002)

The total synthesis of the annonaceous acetogenin, muricatetrocin C
od: Dixon, D, i dr.
Izdano: (2002)

Catalytic stereoselective semihydrogenation of alkynes to E-alkenes.
od: Michaelides, I, i dr.
Izdano: (2013)