A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977

A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 is described using as the key step a stereoselective anomeric oxygen to carbon rearrangement of an alkynyl stannane tetrahydrofuranyl ether derivative mediated by boron trifluoride etherate.

Bibliográfalaš dieđut
Váldodahkkit: Dixon, D, Ley, S, Reynolds, D, Chorghade, MS
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2001

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