Impact of copper on the induction and repair of oxidative DNA damage, poly(ADP-ribosyl)ation and PARP-1 activity.
Copper is an essential trace element involved, among other functions, in enzymatic antioxidative defense systems. However, nonprotein bound copper ions have been shown to generate reactive oxygen species. To gain insight into the discrepancy between the protective properties of copper on the one han...
Hlavní autoři: | Schwerdtle, T, Hamann, I, Jahnke, G, Walter, I, Richter, C, Parsons, J, Dianov, G, Hartwig, A |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2007
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