Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity.

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity.

Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune control. This study examined HCV evolution in 21 HC...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Pfafferott, K, Gaudieri, S, Ulsenheimer, A, James, I, Heeg, M, Nolan, D, John, M, Rauch, A, Mallal, S, Lucas, A, Klenerman, P, Diepolder, H, Lucas, M
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	Public Library of Science 2011

Gelijkaardige items

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity.
door: Katja Pfafferott, et al.
Gepubliceerd in: (2011-02-01)

The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design.
door: von Delft, A, et al.
Gepubliceerd in: (2015)

MULTIPLE NOVEL PEPTIDE EPITOPES IN HCV GENOTYPE-3A IDENTIFIED USING TWO PARALLEL APPROACHES
door: Boehmer, A, et al.
Gepubliceerd in: (2011)

Comprehensive longitudinal analysis of cellular immune responses and viral evolution in a person with acute HCV infection requiring antiviral treatment.
door: Lauer, G, et al.
Gepubliceerd in: (2002)

Influence of host resistance on viral adaptation: hepatitis C virus as a case study
door: Plauzolles A, et al.
Gepubliceerd in: (2015-04-01)

Full-length sequence analysis of HCV genotype-3A reveals novel regions of hypervariability
door: Humphreys, I, et al.
Gepubliceerd in: (2007)

Exhaustion of virus specific CD4+T cells during acute hepatitis C
door: Ulsenheimer, A, et al.
Gepubliceerd in: (2007)

Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection.
door: Fitzmaurice, K, et al.
Gepubliceerd in: (2015)

IL28B GENETIC STATUS IN ASSOCIATION WITH HCV SPECIFIC T-CELL IMMUNITY
door: Bucci, C, et al.
Gepubliceerd in: (2011)

Viral escape mechanisms--escapology taught by viruses.
door: Lucas, M, et al.
Gepubliceerd in: (2001)

Cross-Reactivity to Mutated Viral Immune Targets Can Influence CD8+ T Cell Functionality: An Alternative Viral Adaptation Strategy
door: Jennifer Currenti, et al.
Gepubliceerd in: (2021-10-01)

HIV has a significant impact on the early HCV host-viral responses
door: Danta, M, et al.
Gepubliceerd in: (2006)

Immunology of viral co-infections with HIV.
door: Northfield, J, et al.
Gepubliceerd in: (2005)

HCV genome variability in acute and chronic viral hepatitis C
door: N D Yushchuk, et al.
Gepubliceerd in: (2009-04-01)

Co-localisation of hepatitis C virus drug-resistant mutations and immune-driven adaptations for genotype 1 and 3: relevance to therapy outcome
door: Gaudieri, S, et al.
Gepubliceerd in: (2008)

Determination of HCV genotypes and viral loads in chronic HCV infected patients of Hazara Pakistan
door: Ahmad Habib, et al.
Gepubliceerd in: (2011-10-01)

Features of combined (hbv/hcv-infection) viral lesion of the liver
door: I V Maev, et al.
Gepubliceerd in: (2008-02-01)

Distribution of HCV genotypes and HCV RNA viral load in different regions of Mexico
door: Ricardo Jimenez-Mendez, et al.
Gepubliceerd in: (2010-01-01)

Viral load in interferon treated & untreated patients of HCV
door: Alamzeb Jadoon, et al.
Gepubliceerd in: (2023-08-01)

HCV-Mediated Apoptosis of Hepatocytes in Culture and Viral Pathogenesis.
door: Erica Silberstein, et al.
Gepubliceerd in: (2016-01-01)

Cellular immune responses to HCV core increase and HCV RNA levels decrease during successful antiretroviral therapy.
door: Rohrbach, J, et al.
Gepubliceerd in: (2010)

CORRELATION BETWEEN THE ANTIBODY RESPONSE TOWARD SPECIFIC HCV PROTEINS AND HCV VIRAL LOAD
door: Chiydem Ismailova, et al.
Gepubliceerd in: (2021-04-01)

HCV Specific IL-21 Producing T Cells but Not IL-17A Producing T Cells Are Associated with HCV Viral Control in HIV/HCV Coinfection.
door: Sonya A MacParland, et al.
Gepubliceerd in: (2016-01-01)

HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.
door: Feeney, M, et al.
Gepubliceerd in: (2005)

Immune responses in acute and chronic HCV genotype 3a infection detected by two distinct techniques
door: von Delft, A, et al.
Gepubliceerd in: (2011)

Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.
door: Lucas, M, et al.
Gepubliceerd in: (2007)

Molecular Evaluation of Viral load and Genotype of HCV in Acute and Chronic HCV Patients in Kirkuk City
door: Israa Saadoon, et al.
Gepubliceerd in: (2019-03-01)

Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis.
door: Yannick Simonin, et al.
Gepubliceerd in: (2013-03-01)

Effect of ezetimibe in HCV viral load after liver transplantation
door: Hugo Monrroy-Bravo, et al.
Gepubliceerd in: (2016-09-01)

Transient immunological control during acute hepatitis C virus infection: ex vivo analysis of helper T-cell responses.
door: Ulsenheimer, A, et al.
Gepubliceerd in: (2006)

Angiogenic output in viral hepatitis, C and B, and HCV-associated hepatocellular carcinoma
door: Mohamed A. Abdel Mohsen, et al.
Gepubliceerd in: (2014-09-01)

Comparison of HCV viral load and its genotype distributions in HCV mono- and HIV/HCV co-infected illicit drug users
door: Marzieh Jamalidoust, et al.
Gepubliceerd in: (2017-07-01)

Highly immunogenic virally vectored T-cell vaccines cannot overcome subversion of the T-cell response by HCV during chronic infection
door: Swadling, L, et al.
Gepubliceerd in: (2016)

Highly-immunogenic virally-vectored T-cell vaccines cannot overcome subversion of the T-cell response by HCV during chronic infection
door: Swadling, L, et al.
Gepubliceerd in: (2016)

Anti-hepatitis C virus T-cell immunity in the context of multiple exposures to the virus.
door: Katja Pfafferott, et al.
Gepubliceerd in: (2015-01-01)

Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy.
door: Gaudieri, S, et al.
Gepubliceerd in: (2009)

Extracellular Vesicle Release Promotes Viral Replication during Persistent HCV Infection
door: Yucel Aydin, et al.
Gepubliceerd in: (2021-04-01)

T cell sensitivity and the outcome of viral infection.
door: Walker, L, et al.
Gepubliceerd in: (2010)

Evolution of viral structure.
door: Bamford, D, et al.
Gepubliceerd in: (2002)

The evolution of viral diversity
door: Wikramaratna, P
Gepubliceerd in: (2012)