Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.

During biosynthesis of the clinically used beta-lactamase inhibitor clavulanic acid, one of the three steps catalysed by clavaminic acid synthase is separated from the other two by a step catalysed by proclavaminic acid amidino hydrolase (PAH), in which the guanidino group of an intermediate is hydr...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Elkins, J, Clifton, I, Hernández, H, Doan, L, Robinson, C, Schofield, C, Hewitson, K
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2002