Diffusion MRI at 25: Exploring brain tissue structure and function

Diffusion MRI (or dMRI) came into existence in the mid-1980s. During the last 25. years, diffusion MRI has been extraordinarily successful (with more than 300,000 entries on Google Scholar for . diffusion MRI). Its main clinical domain of application has been neurological disorders, especially for t...

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Main Authors: Le Bihan, D, Johansen-Berg, H
Format: Journal article
Published: 2012
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author Le Bihan, D
Johansen-Berg, H
author_facet Le Bihan, D
Johansen-Berg, H
author_sort Le Bihan, D
collection OXFORD
description Diffusion MRI (or dMRI) came into existence in the mid-1980s. During the last 25. years, diffusion MRI has been extraordinarily successful (with more than 300,000 entries on Google Scholar for . diffusion MRI). Its main clinical domain of application has been neurological disorders, especially for the management of patients with acute stroke. It is also rapidly becoming a standard for white matter disorders, as diffusion tensor imaging (DTI) can reveal abnormalities in white matter fiber structure and provide outstanding maps of brain connectivity. The ability to visualize anatomical connections between different parts of the brain, non-invasively and on an individual basis, has emerged as a major breakthrough for neurosciences. The driving force of dMRI is to monitor microscopic, natural displacements of water molecules that occur in brain tissues as part of the physical diffusion process. Water molecules are thus used as a probe that can reveal microscopic details about tissue architecture, either normal or in a diseased state. © 2011 Elsevier Inc.
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spelling oxford-uuid:74f2f5e5-1897-4bcd-9371-3a66dde072a72022-03-26T20:06:24ZDiffusion MRI at 25: Exploring brain tissue structure and functionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:74f2f5e5-1897-4bcd-9371-3a66dde072a7Symplectic Elements at Oxford2012Le Bihan, DJohansen-Berg, HDiffusion MRI (or dMRI) came into existence in the mid-1980s. During the last 25. years, diffusion MRI has been extraordinarily successful (with more than 300,000 entries on Google Scholar for . diffusion MRI). Its main clinical domain of application has been neurological disorders, especially for the management of patients with acute stroke. It is also rapidly becoming a standard for white matter disorders, as diffusion tensor imaging (DTI) can reveal abnormalities in white matter fiber structure and provide outstanding maps of brain connectivity. The ability to visualize anatomical connections between different parts of the brain, non-invasively and on an individual basis, has emerged as a major breakthrough for neurosciences. The driving force of dMRI is to monitor microscopic, natural displacements of water molecules that occur in brain tissues as part of the physical diffusion process. Water molecules are thus used as a probe that can reveal microscopic details about tissue architecture, either normal or in a diseased state. © 2011 Elsevier Inc.
spellingShingle Le Bihan, D
Johansen-Berg, H
Diffusion MRI at 25: Exploring brain tissue structure and function
title Diffusion MRI at 25: Exploring brain tissue structure and function
title_full Diffusion MRI at 25: Exploring brain tissue structure and function
title_fullStr Diffusion MRI at 25: Exploring brain tissue structure and function
title_full_unstemmed Diffusion MRI at 25: Exploring brain tissue structure and function
title_short Diffusion MRI at 25: Exploring brain tissue structure and function
title_sort diffusion mri at 25 exploring brain tissue structure and function
work_keys_str_mv AT lebihand diffusionmriat25exploringbraintissuestructureandfunction
AT johansenbergh diffusionmriat25exploringbraintissuestructureandfunction