Fetal liver hepcidin secures iron stores in utero

Fetal liver hepcidin secures iron stores in utero

In the adult, the liver-derived hormone hepcidin (HAMP) controls systemic iron levels by blocking the iron-exporting protein ferroportin (FPN) in the gut and spleen, the sites of iron absorption and recycling respectively. Impaired HAMP expression or FPN responsiveness to HAMP result in iron overloa...

Bibliografiset tiedot
Päätekijät:	Kämmerer, L, Mohammad, G, Wolna, M, Robbins, P, Lakhal-Littleton, S
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	American Society of Hematology 2020

Samankaltaisia teoksia

The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload
Tekijä: Mohammad, G, et al.
Julkaistu: (2021)

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis
Tekijä: Lakhal-Littleton, S, et al.
Julkaistu: (2016)

THE ROLES OF HEPCIDIN AND FERROPORTIN IN AUTOCRINE REGULATION OF IRON LEVELS
Tekijä: Lakhal-Littleton, S, et al.
Julkaistu: (2013)

Loss of local hepcidin decreases tumorigenesis in colorectal cancer
Tekijä: Schwartz, A, et al.
Julkaistu: (2017)

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis
Tekijä: Samira Lakhal-Littleton, et al.
Julkaistu: (2016-11-01)

Liver-specific, but not retina-specific, hepcidin knockout causes retinal iron accumulation and degeneration
Tekijä: Baumann, BH, et al.
Julkaistu: (2019)

Iron Stores, Hepcidin, and Aortic Stiffness in Individuals with Hypertension.
Tekijä: Luca Valenti, et al.
Julkaistu: (2015-01-01)

The interplay between iron and oxygen homeostasis with a particular focus on the heart
Tekijä: Lakhal-Littleton, S, et al.
Julkaistu: (2017)

Suppression of plasma hepcidin by venesection during steady-state hypoxia
Tekijä: Talbot, N, et al.
Julkaistu: (2016)

Induced disruption of the iron-regulatory hormone hepcidin inhibits acute inflammatory hypoferremia
Tekijä: Armitage, A, et al.
Julkaistu: (2016)

Hepatic hepcidin/intestinal HIF-2a axis maintains iron absorption during iron deficiency and overload
Tekijä: Schwartz, A, et al.
Julkaistu: (2018)

Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload
Tekijä: Schwartz, A, et al.
Julkaistu: (2018)

Mechanisms of cardiac iron homeostasis and their importance to heart function
Tekijä: Lakhal-Littleton, S
Julkaistu: (2018)

Liver iron concentrations and urinary hepcidin in β-thalassemia
Tekijä: Raffaella Origa, et al.
Julkaistu: (2007-05-01)

Fetal-to-fetal kidney transplantation in utero
Tekijä: Keita Morimoto, et al.
Julkaistu: (2025-03-01)

Regulation of hepcidin expression at high altitude.
Tekijä: Talbot, N, et al.
Julkaistu: (2012)

Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria.
Tekijä: Casals-Pascual, C, et al.
Julkaistu: (2012)

Iron Deficiency as a Therapeutic Target in Cardiovascular Disease
Tekijä: Samira Lakhal-Littleton
Julkaistu: (2019-08-01)

Iron, anemia and hepcidin in malaria.
Tekijä: Spottiswoode, N, et al.
Julkaistu: (2014)

Iron deficiency and supplementation in heart failure
Tekijä: Lakhal-Littleton, S, et al.
Julkaistu: (2024)

Regulation of transepithelial transport of iron by hepcidin
Tekijä: NATALIA P MENA, et al.
Julkaistu: (2006-01-01)

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells
Tekijä: Schwartz, AJ, et al.
Julkaistu: (2021)

Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and β-thalassemia intermedia
Tekijä: Raffaella Origa, et al.
Julkaistu: (2015-05-01)

Lethal fetal stroke in utero
Tekijä: Tzu-Hung Lin, et al.
Julkaistu: (2013-06-01)

Hepcidin and the iron-infection axis.
Tekijä: Drakesmith, A, et al.
Julkaistu: (2012)

Iron, hepcidin and the metal connection.
Tekijä: Olivier eLoréal, et al.
Julkaistu: (2014-06-01)

Iron, anemia and hepcidin in malaria
Tekijä: Natasha eSpottiswoode, et al.
Julkaistu: (2014-05-01)

Transplantation of Amniotic Epithelial Cells into Fetal Rat Liver by In Utero Manipulation
Tekijä: Nanae Takahashi, et al.
Julkaistu: (2002-07-01)

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells
Tekijä: Schwartz, Andrew J., et al.
Julkaistu: (2022)

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells
Tekijä: Schwartz, Andrew J, et al.
Julkaistu: (2022)

Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice
Tekijä: Lakhal-Littleton, S, et al.
Julkaistu: (2019)

Iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension through endothelin-1
Tekijä: Lakhal-Littleton, S, et al.
Julkaistu: (2019)

Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria
Tekijä: Climent Casals-Pascual, et al.
Julkaistu: (2012-11-01)

Urinary Hepcidin Levels in Iron-Deficient and Iron-Supplemented Piglets Correlate with Hepcidin Hepatic mRNA and Serum Levels and with Body Iron Status.
Tekijä: Robert Staroń, et al.
Julkaistu: (2015-01-01)

Iron-regulatory liver hormone hepcidin and its place in the system of congenital immunity
Tekijä: O. A. Smirnov
Julkaistu: (2010-11-01)

Hepcidin and iron metabolism in preterm infants
Tekijä: Sufeng Ruan, et al.
Julkaistu: (2023-04-01)

The role of hepcidin in iron metabolism in athletes
Tekijä: Bajić Zorislava, et al.
Julkaistu: (2019-01-01)

Iron metabolism and iron disorders revisited in the hepcidin era
Tekijä: Clara Camaschella, et al.
Julkaistu: (2020-02-01)

Iron-deficiency anemia results in transcriptional and metabolic remodeling in the heart toward a glycolytic phenotype
Tekijä: Chung, YJ, et al.
Julkaistu: (2021)

Tolerance and Immunity following in Utero Transplantation of Allogeneic Fetal Liver Cells: The Cytokine Shift
Tekijä: H. Sefrioui, J. Donahue, et al.
Julkaistu: (2003-01-01)