Population pharmacokinetic and pharmacodynamic modeling of artemisinin resistance in Southeast Asia

Orally administered artemisinin-based combination therapy is the first-line treatment against uncomplicated P. falciparum malaria worldwide. However, the increasing prevalence of artemisinin resistance is threatening efforts to treat and eliminate malaria in Southeast Asia. This study aimed to chara...

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Detalles Bibliográficos
Autores principales: Lohy Das, J, Dondorp, A, Nosten, F, Phyo, A, Hanpithakpong, W, Ringwald, P, Lim, P, White, N, Karlsson, M, Bergstrand, M, Tarning, J
Formato: Journal article
Publicado: Springer US 2017