Greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses.
To examine the control of pulsatile insulin secretion by an intrapancreatic pacemaker, samples at minute intervals were taken from the portal vein in dogs in vivo and from an isolated perfused pancreas preparation in vitro. Anesthetized dogs had high amplitude pulsatile insulin secretion which was n...
Main Authors: | Matthews, DR, Hermansen, K, Connolly, A, Gray, D, Schmitz, O, Clark, A, Orskov, H, Turner, R |
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Format: | Journal article |
Language: | English |
Published: |
1987
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