Metabolic changes during carcinogenesis: potential impact on invasiveness.

Successful adaptation to varying microenvironmental constraints plays a crucial role during carcinogenesis. We develop a hybrid cellular automation approach to investigate the cell-microenvironmental interactions that mediate somatic evolution of cancer cells. This allows investigation of the hypoth...

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Bibliographic Details
Main Authors: Smallbone, K, Gatenby, R, Gillies, R, Maini, P, Gavaghan, D
Format: Journal article
Language:English
Published: 2007