Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.

Centrosomes act as sites of microtubule growth, but little is known about how the number and stability of microtubules emanating from a centrosome are controlled during the cell cycle. We studied the role of the TACC3-XMAP215 complex in this process by using purified proteins and Xenopus laevis egg...

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Detaylı Bibliyografya
Asıl Yazarlar: Kinoshita, K, Noetzel, T, Pelletier, L, Mechtler, K, Drechsel, D, Schwager, A, Lee, M, Raff, J, Hyman, A
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2005