Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

The Onchocerca ochengi adult implant and Brugia malayi microfilariemic Severe-Combined Immunodeficient (SCID) mouse models are validated screens to measure macrofilaricidal and microfilaricidal activities of candidate onchocerciasis drugs. The purpose of this study was to assess whether 5 daily sub-...

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Bibliographic Details
Main Authors: Sjoberg, HT, Pionnier, N, Aljayyoussi, G, Metuge, HM, Njouendou, AJ, Chunda, VC, Fombad, FF, Tayong, DB, Gandjui, NVT, Akumtoh, DN, Chounna, PWN, Ndzeshang, BL, Lachaud, S, Tekle, F, Quirynen, L, Engelen, M, Baeten, B, Steven, A, Ward, SA, Taylor, MJ, Wanji, S, Turner, JD
Format: Journal article
Language:English
Published: Public Library of Science 2019

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