Falciparum malaria in the north of Laos: the occurrence and implications of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene haplotype SVMNT.

Falciparum malaria in the north of Laos: the occurrence and implications of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene haplotype SVMNT.

OBJECTIVE: The Pfcrt-gene encodes a transmembrane protein located in the Plasmodium falciparum digestive vacuole. Chloroquine resistant (CQR) strains of African and Southeast Asian origin carry the Pfcrt-haplotype (c72-76) CVIET, whereas most South American and Papua New Guinean CQR stains carry th...

Full description

Bibliographic Details
Main Authors:	Dittrich, S, Alifrangis, M, Stohrer, J, Thongpaseuth, V, Vanisaveth, V, Phetsouvanh, R, Phompida, S, Khalil, I, Jelinek, T
Format:	Journal article
Language:	English
Published:	2005

Similar Items

Therapeutic efficacy of artemether-lumefantrine and artesunate-mefloquine for treatment of uncomplicated Plasmodium falciparum malaria in Luang Namtha Province, Lao People's Democratic Republic.
by: Stohrer, J, et al.
Published: (2004)

Pfcrt haplotypes and the evolutionary history of chloroquine-resistant Plasmodium falciparum
by: Gauri Awasthi, et al.
Published: (2012-02-01)

In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).
by: Mayxay, M, et al.
Published: (2007)

New haplotypes of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene among chloroquine-resistant parasite isolates.
by: Nagesha, H, et al.
Published: (2003)

Distribution of the two forms of <it>Plasmodium falciparum </it>erythrocyte binding antigen-175 (eba-175) gene in Lao PDR
by: Rattanaxay Phetsouvanh, et al.
Published: (2003-07-01)

Factors associated with regional bias of pfcrt (plasmodium falciparum chloroquine resistance transporter) haplotypes in Nepal.
by: Banjara, MR, et al.
Published: (2011)

Mutant <it>pfcrt </it>"SVMNT" haplotype and wild type <it>pfmdr1 </it>"N86" are endemic in <it>Plasmodium vivax </it>dominated areas of India under high chloroquine exposure
by: Mallick Prashant K, et al.
Published: (2012-01-01)

A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos.
by: Mayxay, M, et al.
Published: (2003)

Diversity of Plasmodium falciparum chloroquine resistance transporter (pfcrt) exon 2 haplotypes in the Pacific from 1959 to 1979.
by: Chim W Chan, et al.
Published: (2012-01-01)

Large-scale survey for novel genotypes of <it>Plasmodium falciparum </it>chloroquine-resistance gene <it>pfcrt</it>
by: Takahashi Nobuyuki, et al.
Published: (2012-03-01)

Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon
by: Nicaise Tuikue Ndam, et al.
Published: (2017-03-01)

Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum.
by: Stephanie G Valderramos, et al.
Published: (2010-05-01)

Chloroquine-Resistant Haplotype Plasmodium falciparum Parasites, Haiti
by: Berlin L. Londono, et al.
Published: (2009-05-01)

The T76 mutation in the pfcrt gene of Plasmodium falciparum and clinical chloroquine resistance phenotypes in Papua, Indonesia.
by: Maguire, J, et al.
Published: (2001)

The Knock-Down of the Chloroquine Resistance Transporter PfCRT Is Linked to Oligopeptide Handling in Plasmodium falciparum
by: Cecilia P. Sanchez, et al.
Published: (2022-08-01)

Dynamics of <it>pfcrt </it>alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with <it>Plasmodium falciparum</it>
by: Warhurst David C, et al.
Published: (2010-03-01)

Surveillance of Plasmodium falciparum pfcrt haplotypes in southwestern Uganda by high‐resolution melt analysis
by: Kennedy Kassaza, et al.
Published: (2021-02-01)

<i>Plasmodium falciparum</i> Chloroquine-<i>pfcrt</i> Resistant Haplotypes in Brazilian Endemic Areas Four Decades after CQ Withdrawn
by: Rebecca de Abreu-Fernandes, et al.
Published: (2023-05-01)

Chloroquine versus sulfadoxine-pyrimethamine for treatment of Plasmodium falciparum malaria in Savannakhet Province, Lao People's Democratic Republic: an assessment of national antimalarial drug recommendations.
by: Mayxay, M, et al.
Published: (2003)

Pfcrt and pfmdr1 alleles associated with chloroquine resistance in Plasmodium falciparum from Guyana, South America
by: Wallis Best Plummer, et al.
Published: (2004-06-01)

Genetic polymorphisms in Plasmodium falciparum chloroquine resistance genes, pfcrt and pfmdr1, in North Sulawesi, Indonesia
by: Patrick Reteng, et al.
Published: (2017-04-01)

Sequence and gene expression of chloroquine resistance transporter (<it>pfcrt</it>) in the association of <it>in vitro </it>drugs resistance of <it>Plasmodium falciparum</it>
by: Bray Patrick G, et al.
Published: (2011-02-01)

Investigation of the Plasmodium falciparum food vacuole through inducible expression of the chloroquine resistance transporter (PfCRT).
by: Florian Ehlgen, et al.
Published: (2012-01-01)

Functional characterization of the Plasmodium falciparum chloroquine-resistance transporter (PfCRT) in transformed Dictyostelium discoideum vesicles.
by: Janni Papakrivos, et al.
Published: (2012-01-01)

Combined molecular and clinical assessment of Plasmodium falciparum antimalarial drug resistance in the Lao People's Democratic Republic (Laos).
by: Mayxay, M, et al.
Published: (2007)

<it>Plasmodium falciparum </it>isolates from Angola show the S<sub>tct</sub>VMNT haplotype in the <it>pfcrt </it>gene
by: Lutucuta Kosi Florbela JI, et al.
Published: (2010-06-01)

Thiamin deficiency and uncomplicated falciparum malaria in Laos.
by: Mayxay, M, et al.
Published: (2007)

Dynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso
by: Paul Sondo, et al.
Published: (2015-06-01)

A thirteen-year analysis of <it>Plasmodium falciparum </it>populations reveals high conservation of the mutant <it>pfcrt </it>haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon
by: Ngoma Ghyslain, et al.
Published: (2011-10-01)

Sequence analysis of pfcrt and pfmdr1 genes and its association with chloroquine resistance in Southeast Indian Plasmodium falciparum isolates
by: Hiasindh Ashmi Antony, et al.
Published: (2016-06-01)

Fixation of pfcrt chloroquine resistance alleles in Plasmodium falciparum clinical isolates collected from unrest tribal agencies of Pakistan
by: M. F. Nadeem, et al.
Published: (2021-08-01)

Synergism between Pfcrt and Pfmdr1 genes could account for the slow recovery of chloroquine sensitive Plasmodium falciparum strains in Ghana after chloroquine withdrawal
by: Kwame K. Asare, et al.
Published: (2017-01-01)

On the mechanism of chloroquine resistance in Plasmodium falciparum.
by: Mauro Chinappi, et al.
Published: (2010-01-01)

The impact of HIV-associated immunosuppression on the Plasmodium falciparum chloroquine resistance transporter gene (PfCRT) of HIV patients in Akure, Nigeria
by: Iyabo Adepeju Simon-Oke, et al.
Published: (2020-09-01)

High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1.
by: Babiker, H, et al.
Published: (2001)

Prevalence of Plasmodium falciparum chloroquine resistant gene markers, pfcrt-76 and pfmdr1-86, eight years after cessation of chloroquine use in Mwea, Kenya
by: Sabah Ahmed Omar,1 Francis W. Makokha,2,3 Fat’hia Abdo Mohammed,1 Francis T. Kimani,1 Gabriel Magoma3
Published: (2007-10-01)

Chloroquine clinical failures in P. falciparum malaria are associated with mutant Pfmdr-1, not Pfcrt in Madagascar.
by: Valérie Andriantsoanirina, et al.
Published: (2010-10-01)

Pfcrt Gene in Plasmodium falciparum Field Isolates from Muzaffargarh, Pakistan
by: Sumrin Sahar, et al.
Published: (2015-10-01)

An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).
by: Mayxay, M, et al.
Published: (2006)

Plasmodium falciparum in ancient Egypt.
by: Nerlich, A, et al.
Published: (2008)